Abstract #2641

Reliability of Water-Lipid Separation in the Kidney Measured by Accelerated In Vivo Magnetic Resonance Spectroscopic Imaging at 3 T

Ahmad Alhulail^1,2, Mahsa Servati^1,3, Nathan Ooms^1,3, Oguz Akin⁴, Alp Dincer^5,6, M. Albert Thomas⁷, Ulrike Dydak^1,3, and Uzay E Emir^1,8

¹School of Health Sciences, Purdue University, West Lafayette, IN, United States, ²Department of Radiology and Medical Imaging, Prince Sattam bin Abdulaziz University, Al Kharj, Saudi Arabia, ³Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States, ⁴Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, NY, United States, ⁵Department of Radiology, School of Medicine, Acıbadem Mehmet Ali Aydinlar University, Istanbul, Turkey, ⁶Center for Neuroradiological Applications and Research, Acıbadem Mehmet Ali Aydinlar University, Istanbul, Turkey, ⁷Department of Radiology, University of California Los Angeles, Los Angeles, Los Angeles, CA, United States, ⁸Weldon School of Biomedical Engineering, Purdue University, West Lafayette, IN, United States

MRS could be useful for characterization of the renal cell carcinoma by detecting lipid content. However, single-voxel MRS cannot show the distribution of lipids for heterogeneous tumors. We propose a fast MRSI sequence to map the distribution of lipid metabolites within a clinically acceptable time frame at 3T. The proposed MRSI technique provided high-quality data with reproducible quantitative outputs. The coefficient of variance for the quantified fat fraction was less than 1%.

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