The purpose of this study was to assess the ability of hepatocyte fraction on Gd-EOB-DTPA-enhanced MRI for the quantitative evaluation of liver function. 69 patients with cirrhosis and 22 healthy volunteers with normal liver function who underwent Gd-EOB-DTPA enhanced MRI were collected in this study. T1 mapping images were obtained by using the Look-Locker sequences before and 20 minutes after Gd-EOB-DTPA administration, hepatocyte fraction (HeF) and KHep were measured. Our study showed that hepatocyte fraction (HeF and KHep vlaues) based on Gd-EOB-DTPA- enhanced T1 mapping MRI is an efficient diagnostic tool for the quantitative evaluation of liver function.
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