Iron overload in the liver can be assessed with MRI by measurements of T2* and R2*. In this study, we assessed the dynamic range of hepatic T2* values using a high-performance 0.55T, compared to 1.5T, in patients with iron overload. Patients with iron overload had increased dynamic range of T2* values at 0.55T (T2* = 11.8 ± 9.4ms) compared with 1.5T (T2* = 5.7 ± 6.0ms), and the measurements were closely correlated between 0.55T and 1.5T (r = 0.96). The improved field homogeneity at 0.55T may provide value for stratification and monitoring of patients with severe iron overload by T2*.
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