Pancreatic fat has been reported to be closely related to type 2 diabetes risk, hence is the subject of our investigation in a clinical trial. Pancreatic fat changes before and after a 12-week intermittent fasting programme with or without daily probiotic were determined using magnetic resonance imaging (MRI). Two-point Dixon protocol was used to scan patients and manual image-processing method was used to quantify the fat. A significant reduction in pancreatic fat was observed after intermittent fasting, while addition of probiotic did not increase pancreatic fat reduction.
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