Abstract #2503

Comparison of the degree of R1rho dispersion in liver between healthy volunteers and patients with liver disease

Minori Onoda¹, Yu Ueda², Satoshi Kobayashi^1,3,4, Tosiaki Miyati³, Naoki Ohno³, Yudai Shogan¹, Tadanori Takata¹, Yukihiro Matsuura¹, and Toshifumi Gabata⁴

¹Department of Radiological Technology, Kanazawa University hospital, Kanazawa, Japan, ²Philips Japan, Tokyo, Japan, ³Faculty of Health Sciences, Institute of Medical, Pharmaceutical and Health Sciences, Kanazawa University, Kanazawa, Japan, ⁴Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan

In this study, we compared the degree of R1rho dispersion in liver of healthy volunteers and patients with liver disease to better understand the behavior of T1rho in liver. T1rho in normal liver tissue was correlated with the perfusion-independent diffusion coefficient (D) calculated by IVIM analysis, whereas in patients with liver disease, there was no correlation between T1rho and D. Furthermore, there was no significant difference between the R1rho dispersion values in liver between volunteers and patients.

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