Abstract #2464

Is renal blood supply a predictor of protein synthesis in the kidney? A preliminary study in the healthy population

Lihua Chen¹, Ailian Liu¹, Jiangzheng Wang², Zhiwei Shen², Qingwei Song¹, Renwang Pu¹, and Nan Wang¹

¹The First Affiliated Hospital of Dalian Medical University, Dalian, China, ²Philips Healthcare, Beijing, China

3D amide proton transfer weighted (APTw) MR imaging is a novelcontrast-agent-free MRI technique for detection of amide protons in mobile cellular proteins and peptides 1-3.On the other hand, 3D pseudo-continuous arterial spin labeling (3D-pCASL)is amethod to measure renal blood supply and hence potentially a metric for renal function. This study reveals a close association between the vascularity and concentration of mobile cellular proteins in kidney.

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