Abstract #2312

Applicability of automated cardiac phase sorting for phase resolved functional lung (PREFUL) MRI

Lea Behrendt^1,2, Andreas Voskrebenzev^1,2, Filip Klimeš^1,2, Marcel Gutberlet^1,2, Hinrich Winther¹, Till Kaireit^1,2, Tawfik Moher Alsady^1,2, Gesa Pöhler^1,2, Frank Wacker^1,2, and Jens Vogel-Claussen^1,2

¹Institute of Diagnostic and Interventional Radiology, Hannover Medical School, Hannover, Germany, ²Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Hannover, Germany

Phase-resolved functional lung (PREFUL) MRI is a promising contrast agent-free 1H method to derive information about perfusion dynamics in free breathing. The analysis includes the segmentation of a main vessel to determine the perfusion phase for reconstruction of a full cardiac cycle. Since manual segmentation can be challenging and time-consuming, an algorithm for automated phase sorting is desirable. In this study such an algorithm is proposed, tested in 34 patients with CF and CTEPH and compared to manual phase sorting. The algorithm was able to perform segmentation in all cases and showed improved phase sorting compared to manual segmentation.

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