Abstract #2272

In-vitro and in-vivo validation of a pediatric whole heart 4D flow acquisition in 4 minutes with compressed sensing

Takashi Fujiwara¹, Lorna Browne¹, Ladonna Malone¹, Quin Lu², Brian Fonseca³, Michael DiMaria³, and Alex J Barker^1,4

¹Department of Radiology, Section of Pediatric Radiology, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, ²Philips Healthcare NA, San Francisco, CA, United States, ³Department of Pediatrics, Section of Pediatric Cardiology, Children's Hospital Colorado, University of Colorado Anschutz Medical Campus, Aurora, CO, United States, ⁴Department of Bioengineering, University of Colorado Anschutz Medical Campus, Aurora, CO, United States

We investigate the feasibility of the accelerating 4D flow with compressed sensing and online reconstruction in pediatric patients. In-vitro models and imaging in pediatric patients was performed and hemodynamic quantification was compared to conventional approaches. The results demonstrated flow metrics and clinically relevant indices measured by 6-fold accelerated CS were in good agreement with those measured by conventional acceleration techniques, with scan time savings of 30.2%. This suggests the feasibility of using CS 4D flow for pediatric patients in the clinical setting.

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