Abstract #2264

Flow measurement with time of flight (TOF) in patients undergoing carotid revascularization: A comparison with arterial spin labeling (ASL)

Zhensen Chen¹, Li Chen², Manabu Shirakawa¹, Wenjin Liu¹, Dakota Ortega¹, Jinmei Chen¹, Niranjan Balu¹, Theodore Trouard³, Thomas S Hatsukami⁴, Wei Zhou⁵, and Chun Yuan¹

¹Radiology, University of Washington, Seattle, WA, United States, ²Electrical and computer engineering, University of Washington, Seattle, WA, United States, ³Biomedical Engineering, University of Arizona, Tuscon, AZ, United States, ⁴Surgery, University of Washington, Seattle, WA, United States, ⁵Surgery, University of Arizona, Tuscon, AZ, United States

In this study, we assessed the potential of using vasculature features extracted from TOF images as surrogate markers of intracranial blood flow in patients undergoing carotid revascularization surgery and MR imaging prior to, within 48 hours after and 6 months after surgery. The intracranial vasculature features, including total volume, total length and total number of branches etc., on TOF images were extracted using a novel tool named iCafe, and then compared with arterial spin labeling (ASL) cerebral blood flow (CBF) measurement. The results show that TOF-iCafe vasculature features have similar behaviors as ASL CBF over the time points.

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