Abstract #2213

Intra-cardiac flow kinetic energy assessment from 4D flow CMR imaging in pediatric and adult repaired Tetralogy of Fallot

XIAODAN ZHAO¹, LIWEI HU², RONG ZHEN OUYANG², RU SAN TAN^1,3, PING CHAI⁴, MARIELLE FORTIER^3,5, SHUO ZHANG⁶, WEN RUAN¹, SHUANG LENG¹, JUN-MEI ZHANG^1,3, BRYANT JENNIFER¹, LYNETTE LS TEO⁴, ROB VAN DER GEEST⁷, TENG HONG TAN^3,5, JAMES YIP⁴, JU LE TAN^1,3, YUMIN ZHONG², and LIANG ZHONG^1,3

¹National Heart Centre Singapore, Singapore, Singapore, ²Shanghai Children’s Medical Centre, Shanghai Jiaotong University School of Medicine, ShangHai, China, ³Duke-NUS Medical School, Singapore, Singapore, ⁴National University Hospital Singapore, Singapore, Singapore, ⁵KK Women’s and Children’s Hospital, Singapore, Singapore, ⁶Philips Germany, Humburg, Germany, ⁷Department of Radiology, Leiden University Medical Center, Leiden, Netherlands

Whole-heart 4D cardiovascular magnetic resonance (CMR) phase-contrast flow measurement enables qualitative and quantitative assessment of intra-cardiac flow. Its feasibility was investigated in 12 pediatric and 13 adult patients with repaired Tetralogy of Fallot (rTOF). Left ventricular (LV) kinetic energy (KE) and pathline-derived flow components were analyzed. KE parameters were significantly correlated with age, but only LV systolic KE remained significantly different after indexing to LV end-diastolic volume. Pediatric rTOF patients had similar LV ejection fraction, indexed LV volumes and mass, but significantly reduced indexed LV systolic KE, retained inflow and increased delayed ejection flow compared with adults.

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