Abstract #2142

3D whole heart CMRA using an image-navigator framework – a clinical comparison study with CCTA and diaphragmatic navigators

Reza Hajhosseiny¹, Aurélien Bustin¹, Imran Rashid¹, Gastao Cruz¹, Radhouene Neji^1,2, Karl Kunze^1,2, Tevfik F. Ismail¹, Ronak Rajani¹, Pier Giorgio Masci¹, Claudia Prieto¹, and René M. Botnar¹

¹Biomedical Engineering Department, School of Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom, ²MR Research Collaborations, Siemens Healthcare Limited, Frimley, United Kingdom

Conventional diaphragmatic navigator coronary magnetic resonance angiography (d1D-NAV-CMRA) is limited by long and unpredictable acquisition-times and motion related image quality degradation. To overcome these challenges, we have previously proposed an image-navigated non-rigid motion-compensated, undersampled reconstruction CMRA framework (iNAV-CMRA) with <10min acquisition times. Here we investigated the clinical feasibility of 1.2mm³ iNAV-CMRA, comparing its performance, in patients with suspected coronary artery disease, against 1.2mm³ d1D-NAV-CMRA and coronary computed tomography angiography (CCTA). Compared to the d1D-NAV-CMRA, the iNAV-CMRA had a shorter acquisition-time(7:24±0:33min vs. 21:02±7:27min, p<0.0001), with improved coronary vessel-length, vessel-sharpness and image-quality-score, and visually comparable to CCTA.

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