Black Blood Vessel Wall Imaging, a valuable tool to detect abnormalities of intracranial vessel walls, was combined with 3D-ASL, a noninvasive approach for detecting cerebral perfusion, to explore the effects of plaque vulnerability and intracranial stenosis on cerebral perfusion. Absolute and relative values of CBF were determined in regions drawn manually based on the territory of blood supply in ASL images. Multivariate regression analysis indicated plaque vulnerability had no significant impact on perfusion while different degrees of luminal narrowing had statistically differences, signifying intracranial stenosis might be a more critical factor for decreased perfusion.
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