Current myocardial T2-mapping based on either segmented or single-shot readout obtains one 2D slice per breath hold. To overcome the limitations in spatial coverage and breath hold dependence, we report free-breathing 3D isotropic whole-heart T2 mapping using a T2-prepared segmented gradient echo sequence with interleaved scan, which enables quantitative mapping at multiple cardiac phases such as late diastole and systole. We demonstrate the feasibility of this approach with comparison to the conventional techniques in healthy volunteer examination.
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