Abstract #2016

Real-time phase contrast MRI measurements of coughing in patients with Chiari malformation

Rob Lloyd^1,2, Iain Ball³, Marcus Stoodley⁴, and Lynne Bilston^1,2

¹Neuroscience Research Australia, Randwick, Australia, ²Prince of Wales Clinical School, University of New South Wales, Randwick, Australia, ³Philips Australia & New Zealand, North Ryde, Australia, ⁴Department of Clinical Medicine, Macquarie University, Macquarie Park, Australia

Cerebrospinal fluid (CSF) flow, as characterised by real-time PCMRI, may inform surgeons whether a patient with Chiari malformation may benefit from decompression surgery. 5 healthy controls and 7 Chiari patients with (N=4) and without (N=3) coughing headache underwent MRI scanning to measure CSF velocities while coughing. Results suggest that Chiari patients with coughing triggered headaches have increased CSF velocities at the foramen magnum during a cough compared with both controls and patients without headache. This may help understand the mechanisms of coughing triggered headaches and provide a useful indicator for clinicians.

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