Abstract #1827

MR Multitasking-based Dynamic Imaging for Cerebrovascular Evaluation (MT-DICE): Development and Feasibility Study

Zhehao Hu^1,2, Anthony G. Christodoulou¹, Nan Wang^1,2, Yibin Xie¹, Bin Sun³, Xiaoming Bi⁴, Fei Han⁴, Shlee S. Song⁵, Marcel M. Maya⁶, Debiao Li^1,2,7, and Zhaoyang Fan^1,2,7

¹Biomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ²Bioengineering Department, University of California, Los Angeles, Los Angeles, CA, United States, ³Department of Radiology, Fujian Medical University Union Hospital, Fuzhou, China, ⁴Siemens Healthineers, Los Angeles, CA, United States, ⁵Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ⁶Department of Imaging, Cedars-Sinai Medical Center, Los Angeles, CA, United States, ⁷Department of Medicine, University of California, Los Angeles, Los Angeles, CA, United States

Perfusion MR imaging (i.e. DCE, DSC) has evolved as an increasingly common modality for evaluating a variety of cerebrovascular diseases, such as stroke and brain tumors, and susceptibility weighted imaging (SWI) is suitable for detection of intracranial hemorrhage. In this work, we developed an MR MultiTasking based Dynamic Imaging for Cerebrovascular Evaluation (MT-DICE) technique that can provide DCE, DSC and SWI information simultaneously with one 8-minute scan and a single contrast agent injection. Feasibility of MT-DICE was demonstrated in healthy volunteers and patients with hemorrhagic stroke or brain cancer.

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