The occurrence of brain tumor is increasing; it is believed that early detection will prove to be beneficial for its treatment. IVIM has proved to provide valuable information and has been explored for brain tumor in prior studies. In the following study, IVIM analysis for brain tumor detection was performed using a novel Biexponential model with Total Variation regularization function (BE+TV model), and a comparison with established Biexponential model was performed. Improvement in coefficient of variation by 16.5 to 43.4% was observed across IVIM parameter. Perfusion faction was estimated to be reliably with this novel methodology.
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