In order to establish the standard brain regional temperatures in normal and healthy people, we initiated a weekly MR spectroscopy quality assurance program, developed the single voxel MRS thermometry calibration curve with a MRS phantom and scanned 10 normal and healthy right handed men. Five region of interests, hypothalamus, cerebellum, thalamus, frontal lobe, and occipital lobe are selected. Interestingly we found a non-uniform temperature distribution in these ROIs. The hypothalamus and thalamus have the highest temperature while cerebellum has the lowest.
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