Abstract #1599

Association between type 2 diabetes mellitus and characteristics of intracranial atherosclerotic plaque: a high-resolution MRI study

Sheng Jiao¹, Juan Huang², Yan Song², Yuhui Chen³, Chengwen Liu⁴, Jinxia Zhu⁴, Jintao Zhang², and Min Chen²

¹Radiology, Beijing hospital, Beijing, China, ²Radiology, Beijing Hospital, Beijing, China, ³Neurology, Beijing Hospital, Beijing, China, ⁴MR Collaboration, Siemens Healthcare Ltd., Beijing, China

In this study we used high-resolution MRI to image intracranial atherosclerotic plaque more precisely, and then characteristics of plaque were obtained to compare with the blood glycemic (BG) level in Type 2 Diabetes mellitus (T2DM). Results demonstrated that patients with poor BG control had heavier intracranial plaque burden and more vulnerability than the patients without DM. While compared with non-DM, patients with good BG control showed no significant different in plaque burden. It suggested that BG level is an independent risk factor for the vulnerability of the intracranial atherosclerotic plaque.

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