Abstract #1320

REACT-MD: simultaneous non-contrast-enhanced subclavian MRA and fat suppressed direct thrombus imaging (MPRAGE) with a large field-of-view

Masami Yoneyama¹, Shuo Zhang², Yasuhiro Goto³, Michinobu Nagao⁴, Kayoko Abe⁴, Osamu Togao⁵, Isao Shiina³, Kazuo Kodaira³, Yutaka Hamatani³, and Marc Van Cauteren⁶

¹Philips Japan, Tokyo, Japan, ²Philips Healthcare, Hamburg, Germany, ³Department of Radiological Services,, Tokyo Women’s Medical University, Tokyo, Japan, ⁴Department of Diagnostic Imaging and Nuclear Medicine, Tokyo Women’s Medical University, Tokyo, Japan, ⁵Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan, ⁶Philips Healthcare, Best, Netherlands

Direct visualization of the plaques and vessel wall lesions in addition to luminal changes is of clinical importance for management of patients with atherosclerotic disease. In this work, the recently proposed REACT (Relaxation-Enhanced Angiography without Contrast and Triggering) technique was further developed and particularly optimized with Multiple Delays (REACT-MD) to simultaneously provide non-contrast-enhanced MR angiogram and MPRAGE (magnetization prepared rapid gradient echo) type images with uniform background tissue suppression over a large field of view. Initial results in patients showed great promise in detection of luminal changes and plaques for assessment of systemic atherosclerosis in one single scan.

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