Abstract #1313

High resolution spiral simultaneous multi‐slice first‐pass perfusion imaging with whole-heart coverage at 1.5 T and 3 T

Junyu Wang¹, Yang Yang^2,3, Ruixi Zhou¹, Changyu Sun¹, Mathews Jacob⁴, Daniel S. Weller⁵, Frederick H. Epstein^1,6, and Michael Salerno^1,3,6

¹Biomedical Engineering, University of Virginia, Charlottesville, VA, United States, ²Biomedical Engineering and Imaging Institute and Department of Radiology, Icahn School of Medicine at Mount Sinai, New York, NY, United States, ³Medicine, University of Virginia, Charlottesville, VA, United States, ⁴Electrical and Computer Engineering, University of Iowa, Iowa City, IA, United States, ⁵Electrical and Computer Engineering, University of Virginia, Charlottesville, VA, United States, ⁶Radiology, University of Virginia, Charlottesville, VA, United States

First-pass contrast-enhanced myocardial perfusion imaging is a useful noninvasive tool to evaluate patients with known or suspected coronary artery disease, but current techniques are still limited in spatial-temporal resolution and ventricular coverage. We designed a spiral pulse sequence with simultaneous multi-slice (SMS) acquisition and utilized the SMS-L1-SPIRiT reconstruction technique to achieve ultra-high resolution (1.5 mm at 1.5 T and 1.25 mm at 3 T) perfusion imaging with whole-heart coverage. The proposed spiral SMS perfusion acquisition strategy was tested on heathy volunteers and clinical patients. High image quality was demonstrated with an SMS factor of 3 at both 1.5T and 3T.

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