The osteochondral junction (OCJ) is the region where calcified cartilage meets subchondral bone (SCB), and is likely to be highly related to osteoarthritis (OA). However, it is difficult to image OCJ tissues due to their relatively short transverse relaxation times, which cause little or no signal to appear with conventional imaging sequences. In this study, we developed a 3D T1-weighed fast ultrashort echo time cones sequence with fat saturation (FS-UTE-Cones) to generate a high OCJ contrast image of the human knee on a clinical 3T MRI scanner.
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