Abstract #1105

Geometrically accurate imaging of the pial arterial vasculature of the human brain in vivo with high-resolution time-of-flight angiography at 7T

Saskia Bollmann^1,2, Michael I. Bernier^1,2, Simon Daniel Robinson^3,4,5, and Jonathan R. Polimeni^1,2,6

¹Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Charlestown, MA, United States, ²Department of Radiology, Harvard Medical School, Charlestown, MA, United States, ³Centre for Advanced Imaging, The University of Queensland, Brisbane, Australia, ⁴High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, ⁵Department of Neurology, Medical University of Graz, Graz, Austria, ⁶Division of Health Sciences and Technology, Massachusetts Institute of Technology, Cambridge, MA, United States

Non-invasive imaging of the pial arterial vasculature using the inflow-based contrast provided by moving blood water spins requires sufficiently small voxel sizes (160 μm) to maintain high contrast in small pial arteries (200 μm diameter). Additional acquisition of quantitative susceptibility values allows the differentiation of veins and arteries, turning magnetic resonance angiography into true arteriography. Importantly, flow compensation in all phase encoding directions is necessary to assure geometric accuracy, even for small vessels.

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