Abstract #1064

Atherosclerotic Plaques on Perforating Arteries Can be Detected by Vessel Wall Imaging at 7T in Patients with Single Subcortical Infarction

Qingle Kong^1,2,3, Haiqiang Qin⁴, Ning Wei⁵, Jing An⁶, Yan Zhuo^1,2,3, and Zihao Zhang^1,2,3

¹State Key Laboratory of Brain and Cognitive Science, Beijing MR Center for Brain Research, Institute of Biophysics, Chinese Academy of Sciences, Beijing, China, ²University of Chinese Academy of Sciences, Beijing, China, ³CAS Center for Excellence in Brain Science and Intelligence Technology, Beijing, China, ⁴Department of neurology, Beijing Tiantan Hospital, Capital Medical University, Beijing, China, ⁵China National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China, ⁶Siemens Shenzhen Magnetic Resonance Ltd., Shenzhen, China

Branch atheromatous disease (BAD) refers to small, deep brain infarcts that are predominantly caused by the occlusion of perforating arteries, which may lead to single subcortical infarction (SSI). However, there is no in-vivo radiological evidence of plaques in the perforating arteries due to their small caliber. In this study, we used high-resolution black-blood imaging at 7T to display the vessel wall of the anterior choroidal artery (AChA), and analyzed atherosclerotic plaques of AChA in patients with isolated infarcts on the posterior limb of internal capsule. The delineation of AChA plaques provides direct imaging evidence for the etiological diagnosis of BAD.

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