Abstract #1019

Dynamic Water, Fat, R2* and B0 Field Inhomogeneity Quantification Using Multi-Echo Multi-Spoke Radial FLASH

Zhengguo Tan^1,2, Peter Dechent³, Xiaoqing Wang^1,2, Nick Scholand^1,2, Dirk Voit⁴, Jens Frahm^2,4, and Martin Uecker^1,2

¹Diagnostic and Interventional Radiology, University Medical Center Göttingen, Göttingen, Germany, ²German Center for Cardiovascular Research (DZHK), Göttingen, Germany, ³Cognitive Neurology, University Medical Center Göttingen, Göttingen, Germany, ⁴Biomedizinische NMR, Max-Planck-Institute for Biophysical Chemistry, Göttingen, Germany

To achieve dynamic and simultaneous access to R2* relaxation rates, B0 field inhomogeneities and water/fat separation, we developed a model-based reconstruction technique on BART for continuous acquisitions based on undersampled multi-echo multi-spoke radial FLASH. Beside spatial smoothness constraints on coil sensitivity and B0 field maps, L1 wavelet regularization is applied to the water, fat and R2* maps. Preliminary results of brain fMRI data demonstrate significant T2* change from 37 to 67 ms in the occipital visual cortex. In addition, R2* mapping of free-breathing liver with only 15 RF shots per frame (194 ms temporal resolution) reveals increased R2* during inspiration.

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