Abstract #0921

Quantitative 23Na MRI of mild traumatic brain injury: Initial findings

Teresa Gerhalter¹, Rosemary Peralta¹, Mickael Tordjman¹, Julia Zabludovsky¹, Seena Dehkharghani¹, Alejandro Zarate², Soo-Min Shin³, Ilya Aylyarov³, Tamara Bushnick², Jonathan M. Silver⁴, Stephen P. Wall³, Brian S. Im², Ryan Brown¹, Guillaume Madelin¹, and Ivan I. Kirov¹

¹Center for Biomedical Imaging, Department of Radiology, New York University School of Medicine, New York, NY, United States, ²Department of Rehabilitation Medicine, New York University School of Medicine, New York, NY, United States, ³Ronald O. Perelman Department of Emergency Medicine, New York University School of Medicine, New York, NY, United States, ⁴Department of Psychiatry, New York University School of Medicine, New York, NY, United States

In this quantitative sodium MRI study, 24 mild traumatic brain injury (mTBI) and 9 controls were scanned at 3 T. Total sodium content (TSC) was calculated in five different subcortical regions, as well as in global grey and white matter. TSC in mTBI did not differ statistically from controls for the examined regions. Patients with findings on conventional ¹H imaging (e.g. lesions, microhemorrhages) did not differ from patients without such findings in their TSC. More patients and controls are being recruited to strengthen the statistical power of these comparisons.

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