Abstract #0827

Comprehensive Analysis of Bladder Wall Perfusion and Deformation in BPH patients using MRI

Ryan J Pewowaruk¹, David R Rutkowski², Cody J Johnson², Colin K Kim², Shane A Wells², Wade A Bushman³, Diego Hernando^2,4, and Alejandro Roldán-Alzate^1,2,5

¹Biomedical Engineering, University of Wisconsin, Madison, WI, United States, ²Radiology, University of Wisconsin, Madison, WI, United States, ³Urology, University of Wisconsin, Madison, WI, United States, ⁴Medical Physics, University of Wisconsin, Madison, WI, United States, ⁵Mechanical Engineering, University of Wisconsin, Madison, WI, United States

Male urogenital disease is a common problem, and non-invasive methods for diagnosis and disease progression tracking are limited. This study was aimed at developing an MRI-based method to characterize urogenital tissue morphology, bladder-prostate interaction, and blood flow perfusion. These methods were tested in three patients with BPH and three healthy volunteers. Strong correlation between void fraction and prostate volume was found. Future work will be aimed at applying these methods to larger cohorts so that clinical utility may be further understood.

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