Abstract #0735

Incorporating T2-orientational dependence into diffusion-T2 correlation experiments using a tiltable coil

Chantal M.W. Tax¹, Elena Kleban¹, Muhamed Barakovic^1,2,3, Maxime Chamberland¹, and Derek K. Jones¹

¹CUBRIC, Cardiff University, Cardiff, United Kingdom, ²Signal Processing Laboratory 5, Ecole Polytechnique Federale de Lausanne, Lausanne, Switzerland, ³Translational Imaging in Neurology Basel, Department of Biomedical Engineering, University Hospital Basel, Basel, Switzerland

The anisotropy of white matter is reflected in various white matter contrasts. Transverse relaxation rates can be probed as a function of fibre-orientation with respect to the main magnetic field, while diffusion properties are probed as a function of fibre-orientation with respect to the gradient field. While the latter is easy to obtain in the same head position, the former involves reorientation of the subject’s head inside the scanner. In this work we deployed a tiltable RF-coil to study R2 anisotropy of the brain white matter in diffusion-T2 correlation experiments.

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