Calibration scans that acquire coil sensitivity, B0 and B1+ inhomogeneities information play an important role in enabling modern acquisition and reconstruction techniques. This work proposes a unified, rapid calibration sequence termed Physics Calibration (PhysiCal) to obtain accurate B0, Eddy, B1+ and coil sensitivity maps. PhysiCal utilizes a carefully designed mix of full and variable density sampling acquisitions across echoes with synergistic constrained and eigenvalue reconstruction for robust and accurate recovery of whole-brain B0, B1+, Eddy and 32-channel coil sensitivity maps in just 11 seconds at 1 mm x 2 mm x 2mm resolution at 3T.
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