Abstract #0568

The Utility of Amide Proton Transfer-weighted Imaging and Diffusion Kurtosis Imaging in the Diagnosis of Benign and Malignant Breast Lesions

Nan Meng¹, Xuejia Wang², Dongming Han², Jing Sun³, Wenling Liu², Kaiyu Wang⁴, and Meiyun Wang*⁵

¹Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China, ²Department of MRI, the First Affiliated Hospital of Xinxiang Medical University, Weihui, China, ³Department of Pediatrics, Zhengzhou Central Hospital, Zhengzhou University, Zhengzhou, China, ⁴GE Healthcare, MR Research China, Beijing, China, ⁵Department of Radiology, Zhengzhou University People’s Hospital & Henan Provincial People’s Hospital, Zhengzhou, China

Amide proton transfer-weighted imaging (APTWI) has unique advantages in displaying the metabolism of diseased proteins. Diffusion kurtosis imaging (DKI) can quantify the diffusion state water molecules in tissues with a non-gaussian model, thus correcting the deviation of the DWI model and improving the detection of lesions. Our results show that compared with APTWI, the DKI is more effective in the diagnosis of benign and malignant breast tumors.

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