This study aimed to investigate whether LI-RADS v2018 could indicate some prognostic information for high-risk patients with LR-5 hepatocellular carcinoma (HCC). We retrospectively evaluated 125 patients who underwent gadoxetic acid–enhanced MR examination within 1 month before surgical resection for HCC. The Cox proportional hazards model revealed that corona enhancement, peritumoral hypointensity on hepatobiliary phase, multifocality and serum alpha-fetoprotein were independent risk factors for early recurrence. The combined model derived from predictive biomarkers showed good performance, which could be used to effectively predict early recurrence after curative hepatectomy for LR-5 HCC.
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