Lymph node dissections during esophagectomy may be omitted or minimized in patients with esophageal cancer without or with limited lymph node metastases, thereby reducing associated morbidity. A promising technique to detect lymph node metastases is T2*-weighted MRI after the injection of ultrasmall superparamagnetic iron oxide nanoparticles (USPIO, ferumoxtran-10). The aim of this study is to evaluate the feasibility of USPIO-enhanced MRI in the detection of locoregional lymph node metastases in patients with esophageal cancer whom underwent nCRT, and to study the effect of nCRT on the evaluation of USPIO-enhanced MRI.
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