Mahalanobis distance is a feasible multivariate approach. This work compared performances of Mahalanobis distances based on different combinations of metrics in assessing the white matter maturation on neonates and toddlers. Mahalanobis distance based on the combination of diffusion tensor and kurtosis tensor metrics demonstrated various advantages: stronger correlation with the postmenstrual age and higher developmental speeds could be revealed; distances from the developing to the adult brains and the changes from neonates to toddlers were enlarged. Results in the current work suggest that diffusion kurotsis imaging with the Mahalanobis distance would benefit the characterization of white matter maturation.
This abstract and the presentation materials are available to members only; a login is required.