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Abstract #0122

MR-guided neuromodulation of visual networks in Rhesus Monkey at a 3T system

Xiaojing Long1, Yangzi Qiao1, Teng Ma1, Weibao Qiu1, Chao Zou1, Jo Lee1, Yang Liu1, Changjun Tie1, Ye Li1, Lijuan Zhang1, Qiang He2, Xin Liu1, and Hairong Zheng1
1Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China, 2Shanghai United Imaging Healthcare Co., Ltd., Shanghai, China

In this work, we applied BOLD fMRI in Rhesus monkey on a 3T MR system and investigated the functional effects induced by transcranial ultrasound stimulation (TUS) in both the target spot (the primary visual cortex) and the remote interconnected brain regions. We found that TUS can evoke BOLD reaction not only on the region-specific region but also the interconnected areas in the monkey brain. Additionally, our results demonstrated that the temporal features of BOLD time courses of TUS on the primary visual cortex and those of real visual stimulation have no significant difference in the regions of primary visual pathway.

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Abstract