Abstract #0118

To assess and follow-up the mpMRI and prostate volumetric changes after whole prostate MR-guided transurethral prostate ultrasound ablation.

Afshin Azadikhah¹, Holden Wu², Melina Hosseiny², and Steven S Raman²

¹Radiology, University of California, Los Angeles, Los Angeles, CA, United States, ²University of California, Los Angeles, Los Angeles, CA, United States

To evaluate the changes of 3 Tesla (3T) mpMRI and PSA parameters before and during multiple time points after whole gland prostate cancer (PCa) treatment using MRI-guided directional transurethral ultrasound ablation (TULSA). Patients were treated and followed-up for 1, 3, 6 and 12-month in retrospective, cohort, a trial study from October 2017 to February 2019. The mean ADC value, T2W, NPV, PSAD, and prostate volume were significantly decreased after 1 to 12-month follow-up with significant differences. MRI-guided TULSA uses a minimally-invasive transurethral approach, and this appears to be an effective method especially in patients with localized, organ-confined prostate cancer.

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