Natural sleep brain MRI (nsMRI) up to 6 months of life to support early diagnosis in term and preterm infants at high risk for cerebral palsy and other developmental disorders is still far from clinical practice, due to unproven feasibility and quality. We extracted some measures of quality (signal to noise ratio, contrast to noise ratio in a cohort of 23 and 53 infants who underwent sedation or natural sleep brain MR respectively. Most of the quality measures extracted across different MR modalities did not differ between nsMRI and sedation MRI (sMRI) suggesting the feasibility of nsMRI at younger ages.
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