Superparamagnetic Iron Oxide (SPIO) contrast agents are used extensively in molecular imaging studies as a tool to evaluate various cell types. Enabling simultaneous use of multiple contrast agents would greatly improve molecular imaging studies. We utilize a bSSFP MR fingerprinting sequence, combined with an extension of the concentration-dependent linear relationship, to show that concentrations of SPIO and a second contrast agent (ProHance) can be simultaneously quantified.
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