Abstract #4980

Reproducibility of Simultaneous in vivo Blood T1 and T2 Imaging Method

Jialu Zhang^1,2, Dingxin Wang², Xiaotong Zhang¹, Lynn E. Eberly³, Gregory J. Metzger², Donald R. Dengel⁴, David E. Tupper⁵, Anne M. Murray⁶, and Xiufeng Li²

¹Interdisciplinary Institute of Neuroscience and Technology, Qiushi Academy for Advanced Studies, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China, ²Center for Magnetic Resonance Research, School of Medicine, University of Minnesota, Minneapolis, MN, United States, ³Division of Biostatistics, School of Public Health, University of Minnesota, Minneapolis, MN, United States, ⁴Laboratory of Integrative Human Physiology, School of Kinesiology, University of Minnesota, Minneapolis, MN, United States, ⁵Neuropsychology Section, Hennepin County Medical Center, Minneapolis, MN, United States, ⁶Berman Center for Clinical Research Hennepin Health Research Institute, Hennepin Healthcare, Minneapolis, MN, United States

The longitudinal and transverse relaxation time constants of blood vary across subjects, developmental stages, physiological states or specific diseases. We implemented a fast method for simultaneous in vivo measurements of blood T₁ and T₂. Although such an approach has been successfully demonstrated, its repeatability or robustness has not been assessed. We performed a two-session study using our fast in vivo blood T₁ and T₂ imaging method, and the study results are reported in the following.

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