Abstract #4947

Assessment of Hepatic Perfusion Before and After a Meal Challenge Using Pseudo-Continuous Arterial Spin Labeling in MRI: Comparison with Intravoxel Incoherent Motion and Phase Contrast

Saori Watanabe¹, Takashi Hamaguchi¹, Naoki Ohno², Yudai Shogan¹, Yu Ueda³, Tadanori Takata¹, Satoshi Kobayashi^1,2,4, Tosiaki Miyati², and Toshifumi Gabata⁴

¹Department of Radiology, Kanazawa University Hospital, Kanazawa, Japan, ²Faclty of Health Sciences, Institute of Medical, Pharmaceutial and Health Sciences, Kanazawa University, Kanazawa, Japan, ³Philips Japan, Tokyo, Japan, ⁴Department of Radiology, Kanazawa University Graduate School of Medical Sciences, Kanazawa, Japan

To assess hepatic blood flow (HBF) with a noninvasive method, we acquired HBF flow before and after meal ingestion using the pCASL method. In addition, we investigated the relationship of HBF, perfusion-related diffusion coefficient (D*) with intravoxel incoherent motion and portal vein blood flow (PVBF) with phase contrast. For each value of HBF, D*, and PVBF following meal ingestion increased significantly compared with the values prior to ingestion. However, there were no correlations between hepatic blood flow, perfusion-related diffusion coefficient, or portal flow with either pre- or post-ingestion.

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