Abstract #4936

Quantitative Analysis of QSM Image for PD Basal-Cortico Circuit

Zhaoyu Lai¹, Chenfei Ye¹, Junyan Sun^2,3, Tao Wu^2,3, Junjie Liu¹, Pengzheng Zhou¹, Chushu Yang¹, Yuan Fang¹, and Ting Ma^1,3

¹Department of Electronics and Information, Harbin Institute of Technology, Shenzhen, China, ²Department of Neurobiology, Neurology and Geriatrics, Xuanwu Hospital Capital Medical University, Beijing Institute of Geriatrics, Beijing, China, ³National Clinical Research Center for Geriatric Disorders, Beijing, China

Parkinson’s disease is associated with iron accumulation, while quantitative susceptibility mapping can provide quantitative measures of magnetic susceptibility. To investigate the connection about iron deposition and PD etiology or progression, we focused on 16 regions in Basal-Cortico motional circuit by using quantitative susceptibility mapping. Combined with a series of Parkinson’s disease scale score, we derived the relationship between iron content and the scale scores.

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