T1rho is a useful biomarker for the diagnosis of several diseases. Current imaging techniques usually use uniform sampling and require a relatively large number of samples to get reliable estimations of T1rho. We show that the intuitive uniform sampling is not optimal, and propose an optimal sampling strategy. We also propose a fast estimation algorithm, which (with the use of spatial redundancy) provides accurate estimates of the T1rho relaxation map from as few as 3 different spin-lock time samples.
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