Abstract #4433

Markerless real-time motion correction for 2D RARE: reducing artefacts in clinical T2 and FLAIR MRI

Robert Frost^1,2, F. Işik Karahanoğlu^1,2, Camilo Jaimes³, Paul Wighton¹, Richard L. Robertson³, P. Ellen Grant^3,4, M. Dylan Tisdall⁵, and André J. W. van der Kouwe^1,2

¹Athinoula A. Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Boston, MA, United States, ²Department of Radiology, Harvard Medical School, Boston, MA, United States, ³Department of Radiology, Boston Children's Hospital, Harvard Medical School, Boston, MA, United States, ⁴Fetal-Neonatal Neuroimaging and Developmental Science Center, Boston Children's Hospital, Boston, MA, United States, ⁵Radiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, United States

This study investigates high-frequency prospective motion correction (PMC) using markerless face tracking for artefact reduction in clinical T2 and FLAIR MRI. The FOV pose was corrected before the acquisition of each slice in PMC sequences and five subjects were scanned with 1:16 min T2, 4:55 min T2, and 1:50 min FLAIR protocols. The multi-slice segmented RARE sequences showed high sensitivity to changes in head position but use of PMC scans consistently recovered good image quality with higher image sharpness as measured by the Tenengrad metric.

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