Development of quantitative water content mapping in human brain at high magnetic field

The method for quantitative water content mapping of a human brain at high magnetic field was proposed. We demonstrated that B₁^- is proportional to B₁⁺ in a uniform area even on a nonuniform image measured at 4.7T. B₁^-s of the reference phantom and a human brain can be compared by measurable B₁⁺s in uniform areas and water content of human brain can be computed from that comparison. Our method was validated in the experiments of the mixture phantom of H₂O and D₂O. Quantitative water content maps of human brains were obtained by our method.