Abstract #4364

Low Dose PET/MR Imaging in Crohn's Disease

Wei-Jie L Chen^1,2, Christian Park¹, Po-Ling Loh², Scott B Perlman¹, David H Kim¹, Jessica B Robbins¹, and Alan B McMillan^1,3

¹Department of Radiology, University of Wisconsin-Madison, Madison, WI, United States, ²Department of Electrical and Computer Engineering, University of Wisconsin-Madison, Madison, WI, United States, ³Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States

For patients with Crohn’s Disease, reduction of radiation exposure during imaging exams is critical as life-long surveillance is often required. This research aims to reconstruct full dose PET images from low dose and MR images using a deep learning approach. Based on the analysis in twenty patients utilizing Leave-One-Out-Cross-Validation, a 10x reduction from clinical FDG tracer dose is attainable.

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