A new sensitive, non invasive, imaging methods capable of a quantitative detection of Tumour Associated Macrophages (TAM) is herein proposed. The method is based the use Fast Field Cycling (FFC) relaxometers to assess the localization of ferumoxytol in TAM in melanoma tumours. The observed 1/T1 NMRD profiles appear highly dependent on the intra or extra cellular localization of the NPs thus allowing an unambiguous TAM quantification.
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