Abstract #4103

Investigating the feasibility of performing quantitative DCE-MRI in an abbreviated breast examination

Kalina P Slavkova¹, Julie C DiCarlo², Anum K Syed³, John Virostko⁴, Anna G Sorace⁴, and Thomas E Yankeelov^2,3,4

¹Physics, University of Texas at Austin, Austin, TX, United States, ²Institute for Computational Engineering and Sciences, University of Texas at Austin, Austin, TX, United States, ³Biomedical Engineering, University of Texas at Austin, Austin, TX, United States, ⁴Diagnostic Medicine, University of Texas at Austin, Austin, TX, United States

MRI is the most sensitive imaging modality for detecting breast cancer, but its use as a screening tool is limited. There has been recent interest in developing an “abbreviated” breast MRI protocol as a screening protocol, which involves a significantly shorter breast MRI exam that does not compromise diagnostic accuracy. In this work, we evaluate the accuracy of estimating perfusion parameters from dynamic contrast-enhanced MRI data by truncating the data into a series of abbreviated-time courses and comparing the corresponding parameter estimates to the original, full-time course parameter estimates.

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