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Abstract #4096

Comparison of Therapeutic Effect Prediction among Dynamic Perfusion Area-Detector CT, Dynamic Perfusion MR Imaging and FDG-PET/CT in Small Cell Lung Cancer Patients with Limited Disease

Yoshiharu Ohno1,2, Masao Yui3, Shigeharu Ohyu3, Yasuko Fujisawa3, Shinichiro Seki1,2, Takeshi Yoshikawa1,2, Katsusuke Kyotani4, and Takamichi Murakami4,5

1Division of Functional and Diagnostic Imaging Research, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan, 2Advanced Biomedical Imaging Research Center, Kobe University Graduate School of Medicine, Kobe, Japan, 3Canon Medical Systems Corporation, Otawara, Japan, 4Center for Radiology and Radiation Oncology, Kobe University Hospital, Kobe, Japan, 5Division of Radiology, Department of Radiology, Kobe University Graduate School of Medicine, Kobe, Japan

No direct comparisons of therapeutic effect prediction have been performed among dynamic perfusion ADCT, dynamic perfusion MRI and FDG-PET/CT in small cell lung cancer (SLCLC) patients. We hypothesize that multiparametric approach by dynamic CE-perfusion ADCT, MRI and FDG-PET/CT can improve therapeutic effect prediction capability in SCLC patients, when compared with each modality assessment. The purpose of this study was to directly compare the capability for therapeutic outcome prediction among dynamics CE-perfusion ADCT and CE-perfusion MRI assessed by same mathematical method and FDG-PET/CT in SCLC patients assessed as limited disease (LD).

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Abstract