Abstract #4006

Fat quantification using simultaneous, separate water and fat excitation combined with CAIPIRINHA

Beáta Bachratá^1,2, Radim Kořínek³, Bernhard Strasser^1,4, Albrecht Ingo Schmid⁵, Martin Krššák^2,6, Wolfgang Bogner¹, Siegfried Trattnig^1,2, and Simon Daniel Robinson¹

¹Department of Biomedical Imaging and Image-Guided Therapy, High Field MR Centre, Medical University of Vienna, Vienna, Austria, ²Christian Doppler Laboratory for Clinical Molecular MR Imaging, Vienna, Austria, ³Institute of Scientific Instruments of the CAS, Brno, Czech Republic, ⁴Department of Radiology, Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States, ⁵Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, ⁶Department of Internal Medicine III, Division of Endocrinology and Metabolism, Medical University of Vienna, Vienna, Austria

Fat quantification by MRI plays an important role in assessing hepatic steatosis and bone marrow changes. We propose a new method for fat quantification in which multiband pulses are used to separately but simultaneously excite fat and water. CAIPIRINHA encoding allows overlapping images of the two species to be separated. Fat fraction maps can be calculated from fat and water images with appropriate consideration of relaxation times. The proposed method is validated on phantoms with different fat concentrations, where it yields similar fat fraction values to the Dixon approach and single-voxel spectroscopy.

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