We investigated the effect of partial-volume corrections on the liver perfusion and function measured from DCE-MRI data using dual input two compartment uptake model. Following the convection principle in the human body, partial-volume error for hepatic portal vein is determined by taking the ratio of time integrals of venous and arterial input function. We found moderate correlation between the corrected and uncorrected venous plasma flow and a poor correlation between corrected and uncorrected extracellular volume and uptake rate. This indicates that partial-volume effect is significant and should be corrected for in the determination of perfusion and liver function.
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