Abstract #3964

In Vivo Cardiac MR Elastography with a Gravitational Transducer

Ayse Sila Dokumaci¹, Torben Schneider², Daniel Fovargue¹, Emma Burnhope¹, Myrianthi Hadjicharalambous¹, Stefan-Heinz Hoelzl¹, Jelizaveta Sudakova¹, Adela Capilnasiu¹, Marian Troelstra^1,3, Sweta Sethi^1,4, Tevfik Ismail¹, Ralph Sinkus¹, and David Alexander Nordsletten^1,5

¹Division of Imaging Sciences and Biomedical Engineering, King’s College London, London, United Kingdom, ²Philips Healthcare, Guildford, Surrey, United Kingdom, ³Amsterdam UMC, Amsterdam, Netherlands, ⁴Guy's and St.Thomas' NHS Foundation Trust, London, United Kingdom, ⁵Department of Biomedical Engineering and Cardiac Surgery, University of Michigan, Ann Arbor, MI, United States

MR Elastography is beneficial in measuring the stiffness values of tissues which can change in disease. Nevertheless, cardiac MR Elastography is not only challenging from the acquisition side but also from the reconstruction side because of the higher stiffness values expected in the cardiac muscle compared to the other organs in which MR Elastography is commonly applied. Here, we present data in healthy subjects and a patient acquired with the gravitational transducer with a novel synchronising strategy in combination with a single-shot SE-EPI-MRE sequence employing second-order motion compensated motion encoding gradients with and without ZOnal Oblique Multislice Imaging.

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