Olfactory impairments are one of the cardinal non-motor symptoms in Parkinson’s Disease (PD). Functional Connectivity analysis was carried out for olfaction task with floral fragrance (smell 1) and citrus fragrance (smell 2) on 10 PD patients (9M/1F, mean age ± SD=57.7±5.6 years). Main effects depicted heterogeneous connectivity and differential lateralization for both the smells. Amygdala and the thalamus were affected for both the smells in patients with PD and may be attributed to the pathology. Olfaction specificity for hippocampal connectivity in floral smell and for orbitofrontal, insula and anterior cingulate in citrus smell suggest differential recruitment of cognition linked areas.
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